Andrea Di Nisio
Professore AssociatoBiografia
Professore associato di Medicina di laboratorio presso l'Università Pegaso dal 2023.
Dopo la laurea in Biologia, ho conseguito il dottorato in Biologia Evoluzionistica dove ho approfondito gli aspetti relativi all’evoluzione dei gameti maschili. Successivamente sono entrato a far parte dell’equipe del prof. Foresta occupandomi di ricerca nell’ambito dei meccanismi di infertilità maschile e patologieendocrine. Dal 2017 ho iniziato a studiare gli effetti dell’inquinamento da sostanze perfluoroalchiliche (Pfas) sulla salute nell’uomo, approfondendo inparticolare gli aspetti molecolari e i meccanismi di interferenza endocrina. Autoredi diverse pubblicazioni scientifiche su riviste internazionali di settore.
Facoltà
Materia d'insegnamento
Analisi e tecniche di laboratorio applicate allo sport
La medicina di laboratorio nello sport
Ricevimento
da definire
Modalità di prenotazione degli uffici
Pubblicazioni
Pagina IRIS:
https://www.unipegaso.iris.cineca.it/cris/rp/rp02181
Titolo | Anno di pubblicazione | rivista: denominazione |
Lipidomic Profile of Human Sperm Membrane Identifies a Clustering of Lipids Associated with Semen Quality and Function | 2024 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Extragonadal function of follicle-stimulating hormone: Evidence for a role in endothelial physiology and dysfunction | 2024 | MOLECULAR AND CELLULAR ENDOCRINOLOGY |
Decreases in serum PFAS are associated with decreases in serum lipids: A longitudinal study on a highly exposed population | 2024 | SCIENCE OF THE TOTAL ENVIRONMENT |
Observational Cross-Sectional Study on Mediterranean Diet and Sperm Parameters | 2023 | NUTRIENTS |
In vitro binding analysis of legacy-linear and new generation-cyclic perfluoro-alkyl substances on sex hormone binding globulin and albumin, suggests low impact on serum hormone kinetics of testosterone | 2023 | TOXICOLOGY |
Membrane Cholesterol Inhibits Progesterone-Mediated Sperm Function through the Possible Involvement of ABHD2 | 2023 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Ketone Body ? -Hydroxy-Butyrate Sustains Progressive Motility in Capacitated Human Spermatozoa: A Possible Role in Natural Fertility | 2023 | NUTRIENTS |
Seminal Cadmium Affects Human Sperm Motility Through the Stable Binding to Cell Membrane | 2023 | FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
Experimental evidence of a limited impact of new-generation perfluoroalkyl substance C6O4 on differentiating human dopaminergic neurons from induced pluripotent stem cells | 2023 | TOXICOLOGY REPORTS |
Legacy perfluoro-alkyl substances impair LDL-cholesterol uptake independently from PCSK9-function | 2023 | TOXICOLOGY REPORTS |
EDCs: Focus on reproductive alterations in males | 2023 | |
Environmental Impact on the Hypothalamus-Pituitary-Testis Axis | 2023 | |
Sellar and parasellar lesions in the transition age: a retrospective Italian multi-centre study | 2023 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Update on bioethical, medical and fertility issues in gender incongruence during transition age | 2023 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
From Gut Microbiota through Low-Grade Inflammation to Obesity: Key Players and Potential Targets | 2022 | NUTRIENTS |
Vitamin D deficiency: a potential risk factor for cancer in obesity? | 2022 | INTERNATIONAL JOURNAL OF OBESITY |
Exposure to artificial light at night: A common link for obesity and cancer? | 2022 | EUROPEAN JOURNAL OF CANCER |
RS 2247911 polymorphism of GPRC6A gene and serum undercarboxylated-osteocalcin are associated with testis function | 2022 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Impairment of human dopaminergic neurons at different developmental stages by perfluoro-octanoic acid (PFOA) and differential human brain areas accumulation of perfluoroalkyl chemicals | 2022 | ENVIRONMENT INTERNATIONAL |
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds | 2022 | CHEMICAL RESEARCH IN TOXICOLOGY |
Cutaneous Melanoma and Hormones: Focus on Sex Differences and the Testis | 2022 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Comparative Evaluation of the Effects of Legacy and New Generation Perfluoralkyl Substances (PFAS) on Thyroid Cells In Vitro | 2022 | FRONTIERS IN ENDOCRINOLOGY |
Risk factors on testicular function in adolescents | 2022 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Spot-light on microbiota in obesity and cancer | 2021 | INTERNATIONAL JOURNAL OF OBESITY |
Pfas concentrations and cardiometabolic traits in highly exposed children and adolescents | 2021 | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH |
Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome | 2021 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Exposure to Perfluoro-Octanoic Acid Associated With Upstream Uncoupling of the Insulin Signaling in Human Hepatocyte Cell Line | 2021 | FRONTIERS IN ENDOCRINOLOGY |
Systematic Review and Critical Analysis on Dietary Supplements for Male Infertility: From a Blend of Ingredients to a Rationale Strategy | 2021 | FRONTIERS IN ENDOCRINOLOGY |
TERRA: A novel biomarker of embryo quality and art outcome | 2021 | GENES |
Identification of Rare LRP5 Variants in a Cohort of Males with Impaired Bone Mass | 2021 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Spot-light on microbiota in obesity and cancer | 2021 | INTERNATIONAL JOURNAL OF OBESITY |
TERRA: A novel biomarker of embryo quality and art outcome | 2021 | GENES |
Central role of ultrasound in the evaluation of testicular function and genital tract obstruction in infertile males | 2021 | ANDROLOGY |
Dietary Supplements for Female Infertility: A Critical Review of Their Composition | 2021 | NUTRIENTS |
Sperm cholesterol content modifies sperm function and trpv1?mediated sperm migration | 2021 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
E2F1 copy number variations in germline and breast cancer: a retrospective study of 222 Italian women | 2021 | MOLECULAR MEDICINE |
Interference of C6O4 on platelet aggregation pathways: Cues on the new-generation of perfluoro-alkyl substance | 2021 | ENVIRONMENT INTERNATIONAL |
Impact of Endocrine Disruptors on Male Sexual Development | 2021 | |
Sperm DNA Methylation at Metabolism-Related Genes in Vegan Subjects | 2021 | FRONTIERS IN ENDOCRINOLOGY |
A clinical approach to parasellar lesions in the transition age | 2021 | JOURNAL OF NEUROENDOCRINOLOGY |
Editorial: Emerging Chemical Risks for Human Health: Endocrine Disruption by Per- and Poly-Fluorinated Alkyl Substances (PFAS) | 2021 | FRONTIERS IN ENDOCRINOLOGY |
Testosterone is sequestered in dysfunctional adipose tissue, modifying androgen-responsive genes | 2020 | INTERNATIONAL JOURNAL OF OBESITY |
Perfluorooctanoic acid alters progesterone activity in human endometrial cells and induces reproductive alterations in young women | 2020 | CHEMOSPHERE |
Perfluorooctanoic acid alters progesterone activity in human endometrial cells and induces reproductive alterations in young women | 2020 | CHEMOSPHERE |
Dietary Supplements for Male Infertility: A Critical Evaluation of Their Composition | 2020 | NUTRIENTS |
Endocrine Disruption of Vitamin D Activity by Perfluoro-Octanoic Acid (PFOA) | 2020 | SCIENTIFIC REPORTS |
Perfluoro-octanoic acid impairs sperm motility through the alteration of plasma membrane | 2020 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Bisphenols and Male Reproductive Health: From Toxicological Models to Therapeutic Hypotheses | 2020 | FRONTIERS IN ENDOCRINOLOGY |
Increased Cardiovascular Risk Associated with Chemical Sensitivity to Perfluoro- Octanoic Acid: Role of Impaired Platelet Aggregation | 2020 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
Testosterone is sequestered in dysfunctional adipose tissue, modifying androgen-responsive genes | 2020 | INTERNATIONAL JOURNAL OF OBESITY |
Osteocalcin: A Protein Hormone Connecting Metabolism, Bone and Testis Function | 2020 | PROTEIN AND PEPTIDE LETTERS |
Health-Related Lifestyles, Substance-Related Behaviors, and Sexual Habits Among Italian Young Adult Males: An Epidemiologic Study | 2020 | SEXUAL MEDICINE |
Use of Biosimilar Follicle-Stimulating Hormone in Asthenozoospermic Infertile Patients: A Multicentric Study | 2020 | JOURNAL OF CLINICAL MEDICINE |
Caution in the management of SARS-CoV-2 infection in males | 2020 | ANDROLOGY |
Serum anti-HPV antibody titer as a marker of vaccine effectiveness in males with genital infection | 2020 | VACCINES |
Vitamin D and Male Osteoporosis | 2020 | |
Perfluoroalkyl substances and bone health in young men: a pilot study | 2020 | ENDOCRINE |
Effects of endocrine disruptors on fetal testis development, male puberty, and transition age | 2020 | ENDOCRINE |
COMPOSIZIONI COMPRENDENTI UN PEPTIDE IN GRADO DI STIMOLARE LA VIA DEL SEGNALE GPRC6A-DIPENDENTE | 2019 | |
SHBG(141-161) Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and ?-Langerhans cell lines | 2019 | SCIENTIFIC REPORTS |
E2F1 copy number variations contribute to spermatogenic impairment and cryptorchidism by increasing susceptibility to heat stress | 2019 | ANDROLOGY |
E2F1 germline copy number variations and melanoma susceptibility | 2019 | JOURNAL OF TRANSLATIONAL MEDICINE |
Endocrine disruption of androgenic activity by perfluoroalkyl substances: clinical and experimental evidence | 2019 | THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM |
E2F1 copy number variations contribute to spermatogenic impairment and cryptorchidism by increasing susceptibility to heat stress | 2019 | ANDROLOGY |
Water and soil pollution as determinant of water and food quality/contamination and its impact on male fertility 11 Medical and Health Sciences 1114 Paediatrics and Reproductive Medicine Rosario Pivonello | 2019 | REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY |
Obesity and hypovitaminosis D: causality or casualty? | 2019 | INTERNATIONAL JOURNAL OF OBESITY SUPPLEMENTS |
Impact of perfluorochemicals on human health and reproduction: a male’s perspective | 2018 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |
Negative Association between Sclerostin and INSL3 in Isolated Human Osteocytes and in Klinefelter Syndrome: New Hints for Testis-Bone Crosstalk | 2018 | THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM |
Novel insights on testicular volume and testosterone replacement therapy in Klinefelter patients undergoing testicular sperm extraction. A retrospective clinical study | 2018 | CLINICAL ENDOCRINOLOGY |
Calcium-sensing receptor polymorphisms increase the risk of osteoporosis in ageing males | 2018 | ENDOCRINE |
Stabilizing selection on sperm number revealed by artificial selection and experimental evolution | 2018 | EVOLUTION |
Human Papillomavirus Prophylactic Vaccination improves reproductive outcome in infertile patients with HPV semen infection: A retrospective study | 2018 | SCIENTIFIC REPORTS |
Anogenital distance is associated with genital measures and seminal parameters but not anthropometrics in a large cohort of young adult men | 2018 | HUMAN REPRODUCTION |
Copy number variations of E2F1: A new genetic risk factor for testicular cancer | 2017 | ENDOCRINE-RELATED CANCER |
Osteocalcin, a bone-derived hormone with important andrological implications | 2017 | ANDROLOGY |
FSH treatment in infertile males candidate to assisted reproduction improved sperm DNA fragmentation and pregnancy rate | 2017 | ENDOCRINE |
Impaired release of Vitamin D in dysfunctional adipose tissue: New cues on Vitamin D supplementation in obesity | 2017 | THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM |
Human papillomavirus infection and male infertility | 2017 | BIOCHIMICA CLINICA |
Polymorphism rs2274911 of GPRC6A as a Novel Risk Factor for Testis Failure | 2016 | THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM |
Directional postcopulatory sexual selection is associated with female sperm storage in Trinidadian guppies | 2016 | EVOLUTION |
Heat Sensing Receptor TRPV1 Is a Mediator of Thermotaxis in Human Spermatozoa | 2016 | PLOS ONE |
The rs2274911 polymorphism in GPRC6A gene is associated with insulin resistance in normal weight and obese subjects | 2016 | CLINICAL ENDOCRINOLOGY |
Role of vitamin D levels and vitamin D supplementation on bone mineral density in Klinefelter syndrome | 2015 | OSTEOPOROSIS INTERNATIONAL |
Multivariate selection drives concordant patterns of pre- and postcopulatory sexual selection in a livebearing fish | 2015 | NATURE COMMUNICATIONS |
Regulation of sclerostin production in human male osteocytes by androgens: Experimental and clinical evidence | 2015 | ENDOCRINOLOGY |
25-Hydroxyvitamin D insufficiency discriminates cardiovascular risk factors accumulation in peri-pubertal boys undergoing overweight screening | 2015 | ENDOCRINE |
Altered chemokine signalling in endothelial progenitor cells from acute ulcerative colitis patients | 2015 | GASTROENTEROLOGY RESEARCH AND PRACTICE |
HPV Prophylactic Vaccination in Males Improves the Clearance of Semen Infection | 2015 | EBIOMEDICINE |
Mutational screening of NR5A1 gene encoding steroidogenic factor 1 in cryptorchidism and male factor infertility and functional analysis of seven undescribed mutations | 2015 | FERTILITY AND STERILITY |
D-Aspartic acid stimulates steroidogenesis through the delay of LH receptor internalization in a mammalian Leydig cell line | 2015 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION |